C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 5/00 (2006.01) A61K 49/00 (2006.01) A61K 49/06 (2006.01) C07C 281/06 (2006.01) C07D 237/04 (2006.01) C07D 295/32 (2006.01)
Patent
CA 2051815
NOVEL MAGNETIC RESONANCE IMAGING AGENTS Abstract of the Disclosure Novel magnetic resonance imaging agents comprise complexes of paramagnetic ions with hydrazide derivatives of polyaminocarboxylic acid chelating agents. These novel imaging agents are characterized by excellent NMR image-contrasting properties and by high solubilities in physiological solutions. A novel method of performing an MMR diagnostic procedure involves administering to a warm-blooded animal an effective amount of a complex as described above and then exposing the warm-blooded animal to an MMR imaging procedure, thereby imaging at least a portion of the body of the warm-blooded animal.
Mallinckrodt Inc.
Osler Hoskin & Harcourt Llp
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