Magnetic resonance system with implantable components and...

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G01R 33/28 (2006.01) A61B 5/055 (2006.01) G01R 33/34 (2006.01) G01R 33/341 (2006.01) G01R 33/38 (2006.01) G01R 33/465 (2006.01) G01R 33/36 (2006.01)

Patent

CA 2710191

Nuclear magnetic resonance systems and methods of use thereof are provided. The systems employ implantable radiofrequency coils (105) and optionally implantable magnets (101). The systems can employ weak permanent magnets and/or permanent magnets that provide magnetic fields that are much less homogeneous than in conventional systems. This allows, for example, for inexpensive and simple probeheads for nuclear magnetic resonance relaxometry with suitable biosensors. The methods of the present invention allow in- vivo magnetic resonance measurements and, in particular, monitoring of analytes and determination of medical diagnostic information, for example, based on determined magnetic resonance parameters.

Cette invention concerne un système de résonance magnétique nucléaire et des procédés d'utilisation associés. Les systèmes emploient des bobines de radiofréquence implantables et des aimants éventuellement implantables. Les systèmes peuvent utiliser des aimants permanents faibles et/ou des aimants permanents produisant des champs magnétiques qui sont bien moins homogènes que dans les systèmes conventionnels, ce qui permet notamment d'obtenir des têtes de sonde simples peu coûteuses pour la relaxométrie par résonance magnétique nucléaire avec biocapteurs appropriés. Les procédés de l'invention permettent des mesures de résonance magnétiquein vivo et, en particulier, la surveillance d'analytes et la détermination de données concernant le diagnostic médical, notamment d'après les paramètres de résonance magnétique déterminés.

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