Magnetically controllable drug and gene delivery stents

Details Magnetically controllable drug and gene delivery stents Magnetically controllable drug and gene delivery stents

C - Chemistry, Metallurgy

08

L

C08L 101/14 (2006.01) A61F 2/06 (2006.01) A61F 2/90 (2006.01) A61K 9/50 (2006.01) A61K 41/00 (2006.01) A61K 47/30 (2006.01) A61K 48/00 (2006.01) A61L 27/50 (2006.01) A61M 31/00 (2006.01) C08J 3/28 (2006.01) H01F 1/42 (2006.01) H01F 41/00 (2006.01)

Patent

CA 2522625

Magnetizable implantable devices and methods for their use in delivery of therapeutic agents encapsulated or dispersed in a magnetic carrier to a selected site of implantation in a subject are provided. In one embodiment, the device includes a magnetizable stent where segments of the magnetizable compound have been electro-deposited on some of the struts of the stent. Blood flow through the artery brings the therapeutic agent in a magnetic carrier in proximity within the implanted stent. As blood flows through the stent, the therapeutic agent in the magnetic carrier is attracted to the segments of the stent with the magnetizable compound.

L'invention concerne des dispositifs magnétisables implantables et des méthodes d'utilisation de ceux-ci pour la distribution d'agents thérapeutiques encapsulés ou dispersés dans un support magnétique sur un site d'implantation sélectionné chez un sujet.

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