Malaria associated antigen and preparing process thereof

Details Malaria associated antigen and preparing process thereof Malaria associated antigen and preparing process thereof

A - Human Necessities

61

K

167/129

A61K 39/015 (2006.01) C07K 14/445 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1231051

ABSTRACT OF THE DISCLOSURE Disclosed is a novel malaria associated antigen (CRA) and a process for preparation of the antigen. CRA according to the invention can be obtained from Plasmodium-infected erythrocytes by firstly homogenizing Plasmodium-infected erythrocytes, dissolving the thus obtained precipitate by means of a solubilizing agent, and being followed by isolating glycoprotein which can be bound to lectin which can enter into specific combination with terminal mannose, from the supernatant component of the solution. The thus obtained CRA is very useful and effective as a malaria vaccine.

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