C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 39/002 (2006.01) C07K 14/445 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2359610
The present invention relates to a vaccine against malaria comprising a polypeptide having the amino acid sequence of the C-terminal part of the circumsporozoite protein of a Plasmodium species, in which polypeptide one or more pairs of cysteine residues are oxidized, and optionally a suitable carrier and/or adjuvant and/or biodegradable microcapsules for use in humans.
L'invention concerne un vaccin contre la malaria, qui comporte un polypeptide contenant la séquence d'acides aminés de la partie C-terminale de la protéine circumsporozoïtique d'un <u>Plasmodium</u>, ce polypeptide contenant une ou plusieurs paires de résidus cystéine oxydés, et éventuellement un excipient et/ou un adjuvant approprié(s) et/ou des microcapsules biodégradables pour un usage chez l'être humain.
Corradin Giampietro
Roggero Mario
Fetherstonhaugh & Co.
Rmf Dictagene S.a.
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