Malarial aspartic protease inhibitors

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 5/06 (2006.01) A61K 31/13 (2006.01) A61K 31/27 (2006.01) A61K 31/33 (2006.01) A61K 38/05 (2006.01) C07C 215/20 (2006.01) C07C 271/16 (2006.01) C07D 233/54 (2006.01) C07D 233/64 (2006.01) C07D 295/205 (2006.01) C07D 295/215 (2006.01) C07D 403/12 (2006.01) C07K 5/065 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2181551

2,5-Diolpentylamine protease inhibitor compounds are effective as malarial aspartic protease inhibitors. Such compounds and compositions containing such compounds are effective for treatment or prophylaxis of malarial infections.

Cette invention concerne des composés d'inhibiteurs de la protéase 2,5-diolpentylamine qui sont efficaces comme inhibiteurs de la protéase aspartique du paludisme. Ces composés et les compositions contenant ces derniers sont efficaces pour traiter ou prévenir les infections provoquées par le paludisme.

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