Malate dehydrogenase as a target for herbicides

Details Malate dehydrogenase as a target for herbicides Malate dehydrogenase as a target for herbicides

C - Chemistry, Metallurgy

12

N

C12N 15/53 (2006.01) A01H 1/04 (2006.01) A01H 5/00 (2006.01) A01N 61/00 (2006.01) C12N 1/14 (2006.01) C12N 1/15 (2006.01) C12N 1/21 (2006.01) C12N 1/32 (2006.01) C12N 5/10 (2006.01) C12N 9/02 (2006.01) C12N 9/04 (2006.01) C12N 15/09 (2006.01) C12N 15/63 (2006.01) C12N 15/82 (2006.01) C12Q 1/00 (2006.01) C12Q 1/32 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2510561

The invention relates to the use of malate dehydrogenase, the absence of which causes growth retardation and chlorotic leaves and which is coded by the nucleic acid sequence SEQ ID NO:2 or a functional equivalent thereof, as a target for herbicides. Novel nucleic acid sequences comprising SEQ ID NO:2 and functional equivalents of SEQ ID NO:2 are provided in said framework. The invention also relates to the use of said malate dehydrogenase and the functional equivalents thereof in a method for identifying compounds having a herbicidal or growth-regulating effect and the use of the compounds identified via said method as herbicides or growth regulators.

La présente invention concerne l'utilisation de malate déshydrogénase, dont l'absence entraîne des retards de croissance et des feuilles chlorotiques et qui est codée par la séquence d'acides nucléiques SEQ ID NO:2 ou par un équivalent fonctionnel de celle-ci, comme cible pour des herbicides. Dans ce cadre, l'invention concerne également de nouvelles séquences d'acides nucléiques comprenant SEQ ID NO:2 et des équivalents fonctionnels de SEQ ID NO:2. L'invention concerne en outre l'utilisation de ladite malate déshydrogénase et de ses équivalents fonctionnels dans un procédé d'identification de composés présentant une action herbicide ou un effet de régulation de croissance, ainsi que l'utilisation des composés identifiés par ce procédé en tant qu'herbicides ou régulateurs de croissance.

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