Malate salts, and polymorphs of...

Details Malate salts, and polymorphs of... Malate salts, and polymorphs of...

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01) A61K 31/47 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2647346

The present invention is directed to malate salts of (3S,5S)-7-[3-amino-5-methyl- piperidinyl]-l-cyclopropyl-l,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid, and its polymorphs. The present invention is also directed to pharmaceutical compositions comprising the described salts and polymorphs.

La présente invention concerne des malates et des formes polymorphes de l'acide (3S,5S)-7-[3-amino-5-méthyl-pipéridinyl]-1-cyclopropyl-1,4-dihydro-8-méthoxy-4-oxo-3-quinoléine-carboxylique. Elle concerne également des compositions pharmaceutiques comprenant lesdits sels et formes polymorphes.

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