A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/57 (2006.01) A61P 15/16 (2006.01)
Patent
CA 2398063
A formulation for male contraception comprising a progestin prossessing both estrogenic and androgenic properties is remarkably effective for spermatogenesis suppression in males. The progestin Norethisterone (NET), particularly its derivatives Norethisterone acetate and Norethisterone enanthate in sufficient doses induce oligozoospermia or azoospermia in males. Formulations further comprising an androgen, such as a testosterone derivative such as a testosterone ester, particularly testosterone undecanoate, are especially effective male contraceptive formulations.
L'invention concerne une préparation de contraception masculine, comprenant une progestine possédant des propriétés à la fois oestrogènes et androgènes, remarquablement efficaces pour la suppression de la spermatogenèse chez les hommes. La Noréthistérone (NET) à progestine, notamment ses dérivés, l'acétate de Noréthistérone et l'énanthate de Noréthistérone, induisent, en doses suffisantes, l'oligozoospermie ou l'azoospermie chez les hommes. Les préparations comprenant un androgène, tel qu'un dérivé de testostérone tel que l'ester de testostérone, notamment l'indécanoate de testostérone, sont des préparations contraceptives masculines particulièrement efficaces.
Habenicht Ursula-Friederike
Kamischke Axel
Nieschlag Eberhard
Oettel Michael
Ruebig Alexander
Marks & Clerk
Schering Aktiengesellschaft
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