C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/12 (2006.01) A61K 31/505 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2548662
The present invention relates to AZD2171 maleate salt, to particular crystalline forms of AZD2171 maleate salt, to processes for their preparation, to pharmaceutical compositions containing them as active ingredient, to their use in the manufacture of medicaments for use in the production of antiangiogenic and/or vascular permeability reducing effects in warm-blooded animals such as humans, and to their use in methods for the treatment of disease states associated with angiogenesis and/or increased vascular permeability.
L'invention concerne le sel de maléate AZD2171, des formes cristallines particulières du sel de maléate AZD2171, des procédés permettant leur préparation, des compositions pharmaceutiques les contenant en tant que principe actif, leur utilisation dans la fabrication de médicaments utilisés pour produire des effets réduisant la perméabilité antiangiogénique et/ou vasculaire chez des animaux à sang chaud tels que des sujets humains, et leur utilisation dans des méthodes de traitement d'états pathologiques associés à l'angiogénèse et/ou la perméabilité vasculaire accrue.
Astrazeneca Ab
Fetherstonhaugh & Co.
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