Malleable paste for filling bone defects

Details Malleable paste for filling bone defects Malleable paste for filling bone defects

A - Human Necessities

61

L

A61L 27/00 (2006.01) A61K 35/28 (2006.01) A61K 35/32 (2006.01) A61K 38/18 (2006.01) A61L 24/00 (2006.01) A61L 27/08 (2006.01) A61L 27/20 (2006.01) A61L 27/22 (2006.01) A61L 27/36 (2006.01) A61L 27/48 (2006.01) A61L 27/52 (2006.01) A61L 27/54 (2006.01)

Patent

CA 2294686

The invention is directed toward a malleable bone putty and a flowable gel composition for application to a bone defect site to promote new bone growth at the site which comprises a new bone growth inducing compound of demineralized lyophilized allograft bone powder. The bone powder has a particle size ranging from about 100 to about 850 microns and is mixed in a high molecular weight hydrogel carrier, the hydrogel component of the carrier ranging from about 0.3 to 3.0% of the composition and having a molecular weight of about at least 10,000 Daltons. The composition contains about 25% to about 40% bone powder and can be additionally provided with BMP's and a sodium phosphate buffer.

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