Malonate derivatives useful as intermediates for producing...

Details Malonate derivatives useful as intermediates for producing... Malonate derivatives useful as intermediates for producing...

C - Chemistry, Metallurgy

07

D

C07D 263/32 (2006.01) C07D 413/04 (2006.01) C07D 413/12 (2006.01) C07D 417/04 (2006.01) C07D 471/04 (2006.01) C07D 473/00 (2006.01) C07D 487/04 (2006.01) C07D 491/044 (2006.01) C07D 495/04 (2006.01) C07D 498/04 (2006.01) C07D 513/04 (2006.01)

Patent

CA 2263500

Disclosed are novel malonate derivatives of the formula (XIV): (see fig. I ) (wherein R is an optionally substituted aromatic hydrocarbon, an optionally substituted alicyclic hydrocarbon, an optionally substituted heterocyclic group, an optionally substituted condensed heterocyclic group or a group of the formula: Image R1 is a cyclic group, R2 and R3 are hydrogen or lower alkyl, X is O, S or NH, R4 is hydrogen, lower alkyl or hydroxyl; R5 is lower alkyl; and R7 is lower alkyl), useful as intermediates for producing isoxazolidinedione derivatives which have superior hypoglycemic and hypolipidemic actions and are useful for the treatment of diabetes and the complications thereof.

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