C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 261/04 (2006.01) A61K 31/42 (2006.01) A61K 31/4439 (2006.01) A61P 3/00 (2006.01) C07D 413/04 (2006.01)
Patent
CA 2735478
The present invention relates to novel compounds (I), their prodrugs, and the pharmaceutically acceptable salts as well as pharmaceutical compositions containing such compounds useful in treating certain metabolic diseases and diseases modulated by the inhibition of the enzyme malonyl-coenzyme A decarboxylase (malonyl-CoA decarboxylase, MCD). In particular, the invention relates to compounds and compositions and the methods for the prophylaxis, management and treatment of cardiovascular diseases, diabetes, acidosis, and obesity through the inhibition of malonyl-coenzyme A decarboxylase.
Arrhenius Thomas
Chen Mi
Cheng Jie Fei
Dyck Jason R.
Huang Yujin
Chugai Seiyaku Kabushiki Kaisha
Torys Llp
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