Mammalian adipogenic factors

Details Mammalian adipogenic factors Mammalian adipogenic factors

C - Chemistry, Metallurgy

12

Q

C12Q 1/32 (2006.01) A61K 39/395 (2006.01) C07K 1/36 (2006.01) C07K 14/47 (2006.01) C07K 14/475 (2006.01) C07K 14/52 (2006.01) C07K 16/18 (2006.01) C07K 16/24 (2006.01) C12N 15/12 (2006.01) C12Q 1/02 (2006.01)

Patent

CA 2128323

Mammalian adipogenic factors, including purified proteins or glycoproteins, capable of inducing the adipose differentiation of adipogenic cells are disclosed, as are antibodies to such proteins, DNA encoding the proteins and host cells expressing the proteins. A method for determining the susceptibility of a subject to obesity by measuring the levels of one or more adipogenic factors in a biological fluid or tissue extract is also disclosed, as is a method for evaluating an and-obesity drug which comprises contacting the drug with cells capable of producing one or more adipogenic factors and measuring the amount of the factors produced.

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