Mammalian cell preparations optionally transfected with a...

Details Mammalian cell preparations optionally transfected with a... Mammalian cell preparations optionally transfected with a...

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61P 25/00 (2006.01) C12N 5/10 (2006.01)

Patent

CA 2355882

The invention concerns a mammalian cell preparation optionally transfected with at least a gene coding for an active substance capable of being administered to a subject by systemic administration. The invention is characterised in that it does not comprise aggregate of said cells having a size likely to cause temporary or permanent dysfunction in the subject. The invention also concerns pharmaceutical compositions comprising said preparation and an acceptable carrier.

La présente invention a pour objet une préparation de cellules de mammifère éventuellement transfectées avec au moins un gène codant pour une substance active, pour être administrée par voie sytémique chez un sujet, caractérisée en ce qu'elle ne comprend pas d'agrégat desdites cellules d'une taille susceptible d'entraîner chez ledit patient des dysfontionnements transitoires ou permanents. L'invention concerne aussi les compositions pharmaceutiques comprenant une telle préparation et un véhicule acceptable.

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