Mammalian cytokines; related reagents and methods

Details Mammalian cytokines; related reagents and methods Mammalian cytokines; related reagents and methods

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) C07K 14/54 (2006.01) C07K 14/545 (2006.01) C07K 19/00 (2006.01) C12N 5/10 (2006.01) C12N 15/12 (2006.01) C12P 21/02 (2006.01) C12P 21/08 (2006.01) G01N 33/532 (2006.01) G01N 33/543 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2287254

Nucleic acids encoding mammalian, e.g., rodent IL-1.delta., IL-1.epsilon., purified IL-1.delta. and IL-1.epsilon. proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.

L'invention concerne des acides nucléiques codant chez un mammifère (par exemple, rongeur) les protéines suivantes : IL-1.delta., IL-1.epsilon., IL-1.delta. et IL-1.epsilon. purifiées ainsi que des fragments de ces protéines. L'invention concerne aussi des anticorps polyclonaux et monoclonaux, et des procédés liés à l'utilisation des compositions considérées à des fins diagnostiques et thérapeutiques.

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