Mammalian edg-7 receptor homologs

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) C07K 14/705 (2006.01) C12N 5/10 (2006.01) C12N 15/85 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2325049

The present invention is directed to nucleic acid sequence and amino acid sequences for mammalian EDG-7 receptor homologs, and particularly for human EDG-7 receptor homologs. The invention also provides methods for determining agonists and antagonists for EDG-7 receptors in addition to assays, expression vectors, host cells and methods for treating disorders associated with aberrant expression or activity of EDG-7.

La présente invention se rapporte à une séquence d'acide nucléique et à des séquences d'acides aminés codant pour des homologues de récepteurs EDG-7 mammaliens, et notamment pour des homologues de récepteurs EDG-7 humains. L'invention se rapporte également à des procédés de sélection d'agonistes et d'antagonistes associés aux récepteurs EDG-7, ainsi qu'à des analyses, des vecteurs d'expression, des cellules hôtes et des procédés visant à traiter les troubles associés à une expression ou une activité aberrante de EDG-7.

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