Mammalian expression of the bmp-2 family

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/62 (2006.01) C07K 14/51 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/12 (2006.01) C12N 15/18 (2006.01) C12N 15/70 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2082052

2082052 9118047 PCTABS00008 A DNA construct is provided comprising DNA encoding a mature BMP-2 upstream of which is DNA encoding a precursor portion of a mammalian protein other than the BMP-2. Also provided are mammalian expression vectors and hosts containing such a DNA construct and methods for improved expression using such construct.

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