Mammalian interleukin-4

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

530/13, 167/103.

C12N 15/24 (2006.01) A61K 38/20 (2006.01) C07K 14/54 (2006.01) C12N 5/10 (2006.01) C12N 15/02 (2006.01) C12N 15/70 (2006.01) C12P 21/02 (2006.01)

Patent

CA 1341299

Mammalian proteins and muteins thereof, designated interleukin-4s (IL-4s), are provided which exhibit both B cell growth factor activity and T cell growth factor activity. Compounds of the invention include native human and murine IL-4s, muteins thereof, and nucleic acids which are effectively homologous to disclosed cDNAS, and/or which are capable of coding for mammalian IL-4s and their muteins.

523254

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