C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/55 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C07K 14/47 (2006.01) C07K 16/00 (2006.01) C07K 16/40 (2006.01) C12N 5/12 (2006.01) C12N 9/16 (2006.01) C12N 15/63 (2006.01) C12Q 1/42 (2006.01) G01N 33/573 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2410087
The present invention relates to phosphatase polypeptides, nucleotide sequences encoding the phosphatase polypeptides, as well as various products and methods useful for the diagnosis and treatment of various phosphatase- related diseases and conditions. Through the use of a bioinformatics strategy, mammalian members of the MAP kinase phosphatase PTP's and STP's have been identified and their protein structure predicted.
L'invention concerne des polypeptides phosphatase,des séquences de nucléotide codant les polypeptides phosphatase, ainsi que divers produits et procédés servant à établir le diagnostic et le traitement de diverses affections et conditions associées à la phosphatase. Grâce à l'utilisation d'une stratégie bioinformatique, on a réussi à identifier des membres mammifères des protéines thyrosine phosphatase et des sérines thréonine phosphatase de la kinase phosphatase de la carte génétique et leur structure de protéine a été prédite.
Caenepeel Sean
Flanagan Peter
Hill Ronald J.
Manning Gerard
Martinez Ricardo
Osler Hoskin & Harcourt Llp
Sugen Inc.
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