Mammalian sphingosine-1-phosphate phosphatase

Details Mammalian sphingosine-1-phosphate phosphatase Mammalian sphingosine-1-phosphate phosphatase

C - Chemistry, Metallurgy

12

N

C12N 15/55 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C12N 5/00 (2006.01) C12N 5/02 (2006.01) C12N 9/16 (2006.01) C12N 15/00 (2006.01) C12N 15/09 (2006.01) C12N 15/63 (2006.01) C12N 15/70 (2006.01) C12N 15/74 (2006.01)

Patent

CA 2399683

The present invention provides polynucleotides and polypeptides of a murine sphingosine-1-phosphate phosphatase, referred to herein as mSPP1. The polynucleotides and polypeptides are used to further provide expression vectors, host cells comprising the vectors, probes and primers, antibodies against the mSPP1 protein and polypeptides thereof, assays for the presence or expression of mSPP1 and assays for the identification of compounds that interact with mSPP1.

L'invention concerne des polynucléotides et polypeptides d'une sphingosine-1-phosphate phosphatase murine, dénommée ici mSPP1. On utilise ces polynucléotides et polypeptides pour produire des vecteurs d'expression, des cellules hôtes comprenant ces vecteurs, des sondes et amorces, des anticorps dirigés contre mSPP1, ainsi que des polypeptides de ceux-ci. L'invention concerne encore des dosages de la présence ou de l'expression de mSPP1, ainsi que des dosages d'identification de composés interagissant avec mSPP1.

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