Mammalian sphingosine kinase type 2 isoforms, cloning,...

Details Mammalian sphingosine kinase type 2 isoforms, cloning,... Mammalian sphingosine kinase type 2 isoforms, cloning,...

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) A61K 31/70 (2006.01) A61K 38/45 (2006.01) A61K 39/395 (2006.01) C07H 21/04 (2006.01) C12N 1/16 (2006.01) C12N 1/20 (2006.01) C12N 5/00 (2006.01) C12N 5/04 (2006.01) C12N 5/06 (2006.01) C12N 9/12 (2006.01) C12N 15/63 (2006.01) C12P 21/06 (2006.01) C12Q 1/48 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2404965

Nucleic acids encoding mouse and human sphingosine kinase type 2 isoforms, methods for detecting agents or drugs which inhibit or promote sphingosine activity and therapeutic agents containing peptides or antibodies to peptides encoded by such nucleic acids.

L'invention concerne des acides nucléiques codant des isoformes de la sphingosine kinase murine ou humaine de type 2. Elle concerne également des méthodes de détection d'agents ou de médicaments pouvant inhiber ou stimuler l'activité de la sphingosine, et d'agents thérapeutiques contenant des peptides ou des anticorps dirigés contre les peptides codés par lesdits acides nucléiques.

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