Mammalian t1r3 sweet taste receptors

A - Human Necessities – 61 – K

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Details

A61K 38/16 (2006.01) C07K 14/705 (2006.01) C12N 15/12 (2006.01) G01N 33/567 (2006.01)

Patent

CA 2540837

The present invention provides isolated nucleic acid and amino acid sequences of sweet taste receptors, the receptors comprising consisting of a monomer or homodimer of a T1R3 G-protein coupled receptor polypeptide, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sweet and amino acid taste receptors.

La présente invention concerne des séquences isolées d'acides nucléiques et d'acides aminés de récepteurs de goût sucré, les récepteurs étant constitués d'un monomère ou d'un homodimère d'un polypeptide de récepteur T1R3 couplé à une protéine G, des anticorps à ces récepteurs, des procédés de détection de ces acides nucléiques et récepteurs et des procédés pour cribler les modulateurs des récepteurs de goût sucre et d'acides aminés.

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