Man2as as modifiers of the igfr pathway and methods of use

Details Man2as as modifiers of the igfr pathway and methods of use Man2as as modifiers of the igfr pathway and methods of use

G - Physics

01

N

G01N 33/53 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2580478

Human MAN2A genes are identified as modulators of the IGFR pathway and thus are therapeutic targets for disorders associated with defective IGFR function Methods for identifying modulators of IGFR comprising screening for agents that modulate the activity of MAN2A are provided

Des gènes MAN2A humains ont été identifiés comme étant des modulateurs de la voie IGFR et constituant par conséquent des cibles thérapeutiques de troubles associés à une fonction IGFR défectueuse. L'invention concerne des procédés d'identification de modulateurs d'IGFR consistant à cribler des agents modulant l'activité de MAN2A.

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