Mandelic acid derivatives and preparation thereof

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 69/734 (2006.01) C12P 41/00 (2006.01)

Patent

CA 2667287

The invention relates to compounds, compositions, methods of using and processes for producing optically active .alpha.-hydroxy derivatives using a combination of a chemical and biochemical methods. The process comprises reacting an ester compound with a racemic compound in the presence of an enzyme to obtain compounds (compositions and methods). The compounds produced may be useful for starting materials for physiologically active materials, functional materials and the like.

L'invention concerne des composés, des compositions, des procédés d'utilisation et des procédés servant à produire des dérivés .alpha.-hydroxy optiquement actifs en utilisant une combinaison d'un procédé chimique et d'un procédé biochimique. Le procédé consiste à faire réagir un composé ester avec un composé racémique en présence d'une enzyme pour obtenir les composés (compositions et procédés). Les composés produits peuvent être utiles pour des matières de départ pour des substances physiologiquement actives, des substances fonctionnelles et similaires.

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