Manganese and iron based compounds for elastogenesis and...

A - Human Necessities – 61 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 33/26 (2006.01) A61K 33/32 (2006.01) A61K 35/36 (2006.01) A61P 17/00 (2006.01) A61P 17/02 (2006.01)

Patent

CA 2562871

The present invention describes therapeutic compositions comprising one or more minerals, including trivalent iron, divalent manganese and salts thereof, suitable in facilitating synthesis and deposition of connective tissue matrix, particularly rich of elastin and collagen, and mitogenic potential in human dermal fibroblasts. It also describes the phenomenon in which stimulation of elastogenesis by arterial SMC associates with a net decrease in proliferation of these cell types. The present invention also describes methods of treatment of human skin fibroblasts and arterial smooth muscle cells. The therapeutic compositions of the present invention comprise one or more of trivalent iron or divalent manganese or salts thereof and may be combined with an elastic tissue digest.

La présente invention concerne des compositions thérapeutiques comprenant un ou plusieurs minéraux, dont du fer trivalent, du manganèse divalent et des sels de ces minéraux, qui facilitent la synthèse et le dépôt d'une matrice de tissus conjonctifs particulièrement riches en élastine et en collagène, et qui sont dotées d'un potentiel mitogènique dans les fibroblastes cutanés humains. Est également décrit un phénomène dans lequel la stimulation de l'élastogenèse par les cellules de muscle souple artériel est associée à une ralentissement marquée de la prolifération de ces types de cellules. La présente invention concerne en outre des méthodes de traitement de fibroblastes cutanés humains et de cellules de muscle lisse artériel. La composition thérapeutique de la présente invention comprend un ou plusieurs fer trivalent ou manganèse divalent et leurs sels et peut être combinée avec un produit de digestion de tissu élastique.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Manganese and iron based compounds for elastogenesis and... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Manganese and iron based compounds for elastogenesis and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Manganese and iron based compounds for elastogenesis and... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1500674

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.