A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 49/06 (2006.01) A61B 5/055 (2006.01)
Patent
CA 2349342
An MRI contrast medium of improved safety and efficacy is disclosed. The composition includes a source of calcium ions and a source of manganese ions in a ratio of from 2:1 to 40:1 in a vehicle suitable for parenteral administration. A method of enhancing an MRI signal in a mammalian tissue with the foregoing composition is also provided.
L'invention porte sur un milieu de contraste IRM dont l'innocuité et l'efficacité ont été améliorées. La composition comprend une source d'ions calciques et une source d'ions de manganèse dans un rapport de 2:1 à 40:1, et un excipient, cette composition pouvant être appropriée à l'administration parentérale. L'invention porte également sur un procédé visant à intensifier un signal d'IRM dans un tissu mammalien à l'aide de la composition précitée.
Harnish Phillip P.
Seoane Peter R.
Vessey Adele R.
Eagle Vision Pharmaceutical Corporation
Gowling Lafleur Henderson Llp
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