C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
260/228, 260/233
C07H 5/04 (2006.01) A61K 9/127 (2006.01) C07H 13/06 (2006.01)
Patent
CA 1310962
ABSTRACT Novel mannobiose derivative represented by the general formula [I]: Image [ I ] wherein groups of R1 to R5 each represents -OH, -OR6, -NHR6, (R6 represents an acyl group) or a group represented by the following formula (a), (b), (c), (d) or (e), provided that one of R1 to R5 represents -OR6 or -NHR6, one of the other 4 groups of R1 to R5 represents one of the groups represented by the formulae (a) to (e), and the remaining 3 groups of R1 to R5 represent -OH: Image , (a) Image , (b) Image , (c) Image , (d) Image (e) wherein Image represents .alpha. or .beta. bond are provided by the invention. These compounds give liposomes a specific affinity for Kupffer cells of liver, and can be produced industrially.
563127
Hirota Sadao
Hokukoku Shusaburo
Kikuchi Hiroshi
Miyaji Hideki
Tomikawa Munehiro
Daiichi Pharmaceutical Co. Ltd.
Meito Sangyo Co. Ltd.
Swabey Ogilvy Renault
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