Mannose-receptor bearing cells and antigen conjugate for...

A - Human Necessities – 61 – K

Patent

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Details

A61K 35/14 (2006.01) C12N 5/078 (2010.01) C12N 5/0783 (2010.01) A61K 35/26 (2006.01) A61K 35/28 (2006.01) A61K 39/00 (2006.01) A61K 39/385 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2304952

The present invention relates to a product and process for regulating the activity of T cells using a conjugate comprising an antigen and mannose including fully oxidized mannose or partially reduced mannose having aldehydes, and mannose receptor-bearing cells. Methods to administer the products of the present invention are also provided.

L'invention concerne un produit et un procédé de régulation de l'activité des lymphocytes T, au moyen d'un conjugué comprenant un antigène et du mannose constitué de mannose intégralement oxydé ou de mannose partiellement réduit comportant des aldéhydes, et des cellules portant des récepteurs de mannose. Des procédés d'administration desdits produits sont également décrits.

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