Manufacture and expression of structural genes

Details Manufacture and expression of structural genes Manufacture and expression of structural genes

C - Chemistry, Metallurgy

07

H

195/1.22, 195/1.

C07H 21/04 (2006.01) C07H 21/00 (2006.01) C07K 14/675 (2006.01) C12N 1/00 (2006.01) C12N 15/10 (2006.01) C12P 21/00 (2006.01) G01N 33/60 (2006.01)

Patent

CA 1266628

ABSTRACT "THE MANUFACTURE AND EXPRESSION OF STRUCTURAL GENES" Described are rapid and highly efficient procedures for the total synthesis of linear, double stranded DNA sequences of up to about 200 base pairs, which sequences may comprise entire structural genes. Illustratively disclosed is the preparation and expres- sion of manufactured genes, including fusion genes, capable of directing synthesis of human .beta.-endorphin and of proteins which differ from human .beta.-endorphin in terms of the identity or relative position of one or more amino acids. Manufactured genes preferably include codons selected from among alternative codons specifying the same amino acid on the basis of preferen- tial expression in a projected host microorganism (e.g., E. coli) to be tranformed.

427371

Affiliated with

Also associated with

Rating

Manufacture and expression of structural genes does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Manufacture and expression of structural genes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Manufacture and expression of structural genes will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1216755