C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/329.4
C07D 333/34 (2006.01) C07D 333/38 (2006.01)
Patent
CA 1097358
O.Z. 32,364/542 ABSTRACT OF THE DISCLOSURE: 3-Halosulfonylthiophene-carboxylic acid compounds are manufactured by reacting 3-ketothiophane-carb- oxylic acid compounds with sulfonic acid compounds, reacting the end product from the 1st reaction stage with alkali metal poly- sulfides, reacting the end product from the 2nd stage with a dehydrogenating agent and finally reacting the end product from the 3rd stage with halogen and water. The products are starting compounds for the manufacture of drugs, dyes and crop protection agents and have an anti-inflammatory, analgesic and anti-rheumatic action. In particular, the end products I are starting materials for the manufacture of sweeteners which are non-toxic and free from an after-taste, flavor-improving agents, diabetic aids and feedstuffs, and provide the means of a simple and economical syn- thesis of thiophene-saccharins.
293798
Hoffmann Werner
Mueller Norbert
Rossy Phillip A.
Basf Aktiengesellschaft
Robic Robic & Associes/associates
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