Manufacture of a cyclic acid

Details Manufacture of a cyclic acid Manufacture of a cyclic acid

C - Chemistry, Metallurgy

07

D

C07D 233/32 (2006.01)

Patent

CA 2316529

A process for the production of 2-oxo-1,3-dibenzyl-cis-4,5- imidazolidinedicarboxylic acid starting from meso-2,3-bis(benzylamino)- succinic acid dialkali metal salt comprises reacting reacting meso-2,3-bis(benzylamino)- succinic acid dialkali metal salt with triphosgene in a two-phase solvent system consisting of an aqueous alkali hydroxide solution and an organic solvent at a temperature not exceeding about 50°C and converting the 2-oxo-1,3-dibenzyl-cis-4,5- imidazolidinedicarboxylic acid dialkali metal salt, which results therefrom and which is present in the aqueous phase, into the desired 2-oxo-1,3-dibenzyl-cis-4,5-imidazolidinedicarboxylic acid by acidification. The product is an important intermediate in the mufti-stage process for the manufacture of biotin (vitamin H).

Affiliated with

Also associated with

Rating

Manufacture of a cyclic acid does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Manufacture of a cyclic acid, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Manufacture of a cyclic acid will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1497328