Manufacture of n-[3,4-dimethylphenyl]-d-ribamine

B - Operations – Transporting – 01 – J

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260/601.2

B01J 23/72 (2006.01) C07D 487/04 (2006.01)

Patent

CA 1101887

ABSTRACT OF THE DISCLOSURE: N-[3,4-Dimethylphenyl]-N-D-ribamine of the formula Image is manufactured by catalytic hydrogenation of D-ribonic acid ?-lactone in an organic solvent and in the presence of 3,4,3',4'-tetramethylazoxybenzene, 3,4,3',4'-tetramethyl- hydrazobenzene or 3,4,3', 4'-tetramethylazobenzene.

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