Manufacturing method of optically-active 1,2-diols

Details Manufacturing method of optically-active 1,2-diols Manufacturing method of optically-active 1,2-diols

C - Chemistry, Metallurgy

12

P

195/129, 195/65

C12P 41/00 (2006.01) C12P 7/18 (2006.01)

Patent

CA 1336415

A process of manufacturing optically active (S) 1,2-diols, wherein (R)-1,2-diols represented by the general formula [I] Image [I] (where: R represents a substituted or unsubstituted alkyl group, alkenyl group, aryl group or aralkyl group) or a mixture of diols of the general formula [I] and (S) 1,2-diols represented by the general formula [II] Image [II] (Where: R represents the same as above) having an opposite configuration to the general formula [I] is subjected to the action of a microorganism capable of selectively metabolizing the diols of the general formula [I] , or capable of converting the diols of the general formula [I] into the diols of the general formula [II] , or having the both capabilities, and the formed and accumulated (S)-1,2-diols of the general formula [ II] is collected. According to the present invention, optically active (S)-1,2-diols can be produced commercially and advantageously.

584066

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