Map kinases: polypeptides, polynucleotides and uses thereof

Details Map kinases: polypeptides, polynucleotides and uses thereof Map kinases: polypeptides, polynucleotides and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) A61K 38/45 (2006.01) A61K 45/00 (2006.01) C07K 16/40 (2006.01) C12N 9/12 (2006.01) C12Q 1/48 (2006.01) G01N 33/573 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2267656

A substantially pure stress-activated protein kinase comprising the amino acid sequence (I) or a variant, fragment, fusion or derivative thereof, or a fusion of a said variant or fragment or derivative. The above stress-activated protein kinase and the related stress-activated protein kinase SAPK3 are useful in screening assays for drugs.

L'invention concerne une protéine kinase activée par le stress sensiblement pure, comprenant la séquence d'acides aminés (I), ou un variant, un fragment, une fusion ou un dérivé de ladite protéine kinase, ou une fusion dudit variant, fragment ou dérivé. Ladite protéine kinase activée par le stress et la protéine kinase activée par le stress SAPK3 voisine sont utiles pour cribler des médicaments.

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