Mapk7 as modifier of branching morphogenesis and methods of use

Details Mapk7 as modifier of branching morphogenesis and methods of use Mapk7 as modifier of branching morphogenesis and methods of use

C - Chemistry, Metallurgy

12

Q

C12Q 1/48 (2006.01) C07K 14/715 (2006.01) C12N 9/12 (2006.01) C12Q 1/68 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2502684

Human MAPK7 genes are identified as modulators of branching morphogenesis, and thus are therapeutic targets for disorders associated with defective branching morphogenesis function. Methods for identifying modulators of branching morphogenesis, comprising screening for agents that modulate the activity of MAPK7 are provided.

L'invention concerne des gènes MAPK7 humains identifiés comme modulateurs de la morphogenèse de ramification, qui constituent donc des cibles thérapeutiques pour les troubles associés à une fonction déficiente de cette morphogenèse. L'invention concerne également des procédés relatifs à l'identification de modulateurs de ladite morphogenèse, qui consistent à rechercher des agents modulant l'activité du gène MAPK7.

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