Marked maleimide compounds, method for preparing same and...

C - Chemistry – Metallurgy – 07 – D

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07D 401/12 (2006.01) A61K 51/04 (2006.01) A61K 51/08 (2006.01) C07D 401/06 (2006.01)

Patent

CA 2491193

The invention concerns maleimide compounds marked with Fluor 18 of general formula (I), wherein: m represents an integer from 0 to 10; n represents an integer from 1 to 10; Y represents a group selected among optionally substituted heterocyclic, monocyclic or bicyclic groups; X represents a radical of formula (U) ¿a? -((CR¿1?R¿2?) ¿b? -(V) ¿c?)¿d ?-((CR¿3?R¿4?) ¿e?- (W) ¿f?) ¿g?-, wherein: a, b, c, d, e, f, g represent each independently an integer from 1 to 10; 0 A 10; U, V and W represent each independently -NR¿1?-, -O-, -S-,formula (II), ethynyl, -CR¿1?=CR¿2?-, -(C=0)-, -(C=S)-, -C=NR¿1?)-, -C(=0) 0-, -(C=S) S-, -C(=NR¿1?)NR¿2?-, -CR¿1?R¿2?-, -CR¿1?OR¿2?-, -CR¿1?NR¿2?R¿3?. The invention also concerns a method for preparing said compounds, their use for marking macromolecules and complexes of said compounds with a macromolecule. The invention further concerns a kit for analysis, detection, or diagnosis using said complexes. The invention finally concerns the use of the complexes in a medical imaging method such as position emission tomography (PET).?¿

Composés de maléimide marqués par le fluor 18 de formule générale (I) :(FORMULE)dans laquelle :- m représente un nombre entier de 0 à 10 ;- n représente un nombre entier de 1à 10 ;- Y représente un groupe choisi parmi les groupes hétérocycliques monocycliques ou bicycliques, éventuellement, substitués ; - X représente un radical de formule : (U)a -((CR1R2) b -(V) c) d ((CR3R4) e- (W)f) g-dans laquelle :- a, b, c, d, e, f, g représentent chacun indépendamment un nombre entier de 0 à 10 ;- U, V et W représentent chacun indépendamment -NR1#191- , - O -, -S- ,(FORMULE) , éthynyle, -CR1=CR2- , -(C=0)- , -(C=S)- , -C=NR1)- , -C=0) 0- , -(C=S) S- , -C(=NR1)NR2- , -CR1R2- , -CR1OR2- , -CR1NR2R3- .Procédé de préparation de ces composés ; leur utilisation pour le marquage de macromolécules et complexes de ces composés avec une macromolécule.Trousse d'analyse et de détection, ou de diagnostic comprenant lesdits complexes.Utilisation des complexes dans un procédé d'imagerie médicale tel que la tomographie par émission de positons (TEP).

No associations

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Marked maleimide compounds, method for preparing same and... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Marked maleimide compounds, method for preparing same and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Marked maleimide compounds, method for preparing same and... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1737561

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.