C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C40B 30/04 (2006.01) C07H 21/04 (2006.01) C40B 40/06 (2006.01)
Patent
CA 2734519
A method for assessment of the suitability of a target therapy for a gas-trointestinal-related disorder such as ulcera-tive colitis, in a subject evaluates the pres-ence, absence, and/or magnitude of expres-sion of one or more genes in a 20- or 5--member gene panel in a sample. The method enables identification of the effec-tiveness of target therapies prior to starting a patient on such therapies
L'invention concerne un procédé pour évaluer la pertinence d'une thérapie cible pour un trouble de type gastro-intestinal, notamment une recto-colite hémorragique, chez un patient. Ce procédé permet d'évaluer la présence, l'absence, et/ou l'amplitude d'expression d'un ou de plusieurs gènes appartenant à un ensemble de 20 ou 5 gènes contenu dans un échantillon. Ce procédé permet d'identifier l'efficacité de thérapies cibles avant qu'un patient commence à être traité par de telles thérapies.
Baribaud Frederic
Li Xilin Katherine
Centocor Ortho Biotech Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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