Markers for roscovitine

Details Markers for roscovitine Markers for roscovitine

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2519491

The present invention relates to pharmacodynamic markers for CDKIs including the candidate 2, 6, 9-tri-substituted purine known as roscovitine. The identity of these markers facilitates the convenient identification of roscovitine-like activity both in vitro and in vivo.

L'invention concerne des marqueurs pharmacodynamiques pour des inhibiteurs de kinases dépendantes des cyclines (CDKI), notamment le candidat purine 2, 6, 9-tri-substitutée connu en tant que roscovitine. L'identité de ces marqueurs facilitent l'identification de l'activité de type roscovitine à la fois in vitro et in vivo.

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