Maspin, a novel serpin with tumor suppressing activity

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/15 (2006.01) A61K 31/70 (2006.01) A61K 38/57 (2006.01) A61K 39/00 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 14/81 (2006.01) C07K 16/38 (2006.01) C07K 19/00 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/48 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2143188

An isolated DNA encoding a polypeptide substantially identical to maspin (SEQ ID NO: 1); a substantially purified pre- paration of maspin; an antibody specific for maspin; and use of such DNAs and antibodies in diagnostic, screening, and therap- eutic methods.

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