Mass spectrometer

H - Electricity – 01 – J

Patent

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Details

H01J 49/00 (2006.01)

Patent

CA 2570174

A method of searching for potentially unknown metabolites of pharmaceutical compounds is disclosed. The accurate mass of a pharmaceutical compound will generally be known and can be rendered in the form of an integer nominal mass or mass to charge ratio component and a decimal mass or mass to charge ratio component. Possible metabolites are searched for on the basis of having a decimal mass or mass to charge ratio component which is substantially very similar to the decimal mass or mass to charge ratio of the parent pharmaceutical compound.

La présente invention concerne un procédé pour rechercher des métabolites potentiellement inconnus de composés pharmaceutiques. La masse précise d'un composé pharmaceutique est en général connue et peut être représentée sous la forme d'une composante rapport masse ou masse nominale entière sur charge et d'une composante rapport masse ou masse décimale sur charge. Des métabolites possibles sont recherchés en se basant une composante rapport masse ou masse décimale sur charge qui est sensiblement similaire au rapport masse ou masse décimale sur charge du composé pharmaceutique parent.

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