C - Chemistry – Metallurgy – 40 – B
Patent
C - Chemistry, Metallurgy
40
B
C40B 40/08 (2006.01) C07H 21/00 (2006.01) C12N 15/12 (2006.01) C12Q 1/68 (2006.01) C40B 30/02 (2006.01) C40B 50/02 (2006.01)
Patent
CA 2548017
The invention provides materials and methods for detecting the expression of ABC transporter genes. The materials include sets of primers and PCR amplicons. The sets of primers are used to generate PCR amplicons, wherein each PCR amplicon is a unique portion of an ABC transporter gene. The methods of the invention include hybridization assays, such as DNA microarrays. Kits and assays for the detection of ABC transporter gene expression are also provided by the invention. In addition, the use of the materials and methods of the invention in drug screening assays is provided.
L'invention porte sur des matériaux et sur des procédés de détection de l'expression des gènes transporteurs ABC. Les matériaux comprennent des ensembles d'amorces et d'amplicons de PCR. Les ensembles d'amorces sont utilisés pour générer des amplicons de PCR, chaque amplicon de PCR étant une partie unique d'un gène transporteur ABC. Les procédés de l'invention comprennent des procédés d'hybridation telles que des microréseaux d'ADN. L'invention porte également sur des kits et des dosages utiles dans la détection de l'expression des gènes transporteurs ABC. L'invention porte, de plus, sur l'utilisation de matériaux et des procédés précités dans les méthodes de criblage de médicaments.
Lee David K. H.
Shipman Robert C.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Noab Biodiscoveries Inc.
LandOfFree
Materials and methods for analysis of atp-binding cassette... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Materials and methods for analysis of atp-binding cassette..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Materials and methods for analysis of atp-binding cassette... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1994726