C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/86 (2006.01) A01K 67/027 (2006.01) A61K 48/00 (2006.01) A61P 25/24 (2006.01) C07K 14/47 (2006.01) C12N 15/12 (2006.01) C12Q 1/00 (2006.01)
Patent
CA 2704786
The invention provides materials and methods for p11-mediated therapy of psychiatric disorders. The invention provides vectors for increasing p11 expression and methods of treating a mammal with one or more symptoms of a psychiatric disorder. The invention also provides methods for improving a mammal's responsiveness to treatment for a psychiatric disorder. The invention further provides model animals for depression and depression therapy.
L'invention concerne des matériaux et des procédés utilisables en vue d'une thérapie à médiation par le gène p11 de troubles psychiatriques. L'invention concerne des vecteurs capables de renforcer l'expression du gène p11, ainsi que des procédés de traitement d'un mammifère présentant un ou plusieurs symptômes d'un trouble psychiatrique. L'invention concerne également des procédés d'amélioration de la réactivité d'un mammifère au traitement d'un trouble psychiatrique. L'invention concerne encore des modèles animaux de la dépression et de la thérapie de la dépression.
Alexander Brian L.
Kaplitt Michael
Cornell University
Ridout & Maybee Llp
LandOfFree
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