Materials and methods for hypothermic collection of whole blood

Details Materials and methods for hypothermic collection of whole blood Materials and methods for hypothermic collection of whole blood

A - Human Necessities

01

N

A01N 1/02 (2006.01) A61K 35/00 (2006.01)

Patent

CA 2719825

The present invention relates to materials and methods for hypothermic collection of whole blood, and components thereof, which can extend the holding time of blood beyond the current useable limit. Additionally, blood can be drawn directly into a hypothermic preservation solution without the addition of standard anticoagulants. This is enabled by providing sustained cellular viability under hypothermic conditions using a nutrient matrix devoid of animal proteins and containing energy substrates, free-radical scavengers, and impermeants that is ionically balanced for storage of biologic materials at low temperatures to prevent cellular stress-induced apoptosis.

La présente invention concerne des matériels et des procédés pour le prélévement hypothermique de sang total, ainsi que de ses composants, qui peuvent prolonger la durée de conservation du sang au-delà de la limite d'utilisation actuelle. De plus, le sang peut être prélevé et directement introduit dans une solution de conservation hypothermique sans ajout d'anticoagulants standard. Pour ce faire, on garantit la viabilité cellulaire prolongée dans des conditions hypothermiques en utilisant une matrice nutritive exempte de protéines animales, qui contient des substrats énergétiques, des désactivateurs de radicaux libres ainsi que des agents imperméables, et qui est équilibrée sur le plan ionique, pour la conservation de matériels biologiques à basse température de manière à prévenir l'apoptose induite par le stress cellulaire.

Affiliated with

Also associated with

Rating

Materials and methods for hypothermic collection of whole blood does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Materials and methods for hypothermic collection of whole blood, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Materials and methods for hypothermic collection of whole blood will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1569118