Materials and methods for identifying and analyzing...

Details Materials and methods for identifying and analyzing... Materials and methods for identifying and analyzing...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C12N 15/10 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2319111

The present invention is directed to materials and methods for the identification and analysis of intermediate tandem repeat sequences in DNA, wherein an intermediate tandem repeat (ITR) sequence is a region of a DNA sequence containing at least one five to seven base repeat unit appearing in tandem at least two times. DNA markers to highly polymorphic ITR loci in the human genome are identified and analyzed, using particularly preferred embodiments of the materials and methods of the present invention.

La présente invention concerne des matières et des procédés d'identification et d'analyse de séquences à répétition en tandem intermédiaire dans l'ADN, une séquence à répétition en tandem intermédiaire (ITR) étant une région de séquence d'ADN contenant au moins une unité de répétition à base comprise entre cinq et sept, apparaissant en tandem au moins deux fois. On identifie et analyse des marqueurs d'ADN dans des loci d'ITR hautement polymorphiques en faisant appel à des modes de réalisation particulièrement préférés des matières et procédés de la présente invention.

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