Materials and methods for improved immunoglycoproteins

Details Materials and methods for improved immunoglycoproteins Materials and methods for improved immunoglycoproteins

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61K 39/00 (2006.01) C12P 21/00 (2006.01) C07K 16/00 (2006.01)

Patent

CA 2720774

Immunoglycoproteins, including antibodies, with improved ADCC and altered glycosylation patterns are provided. Also provided are cell culturing methods and media for producing such immunoglycoproteins, and therapeutic uses of such im-munoglycoproteins.

L'invention concerne des immunoglycoprotéines, comprenant des anticorps, ayant une ADDC améliorée et des motifs de glycosilation altérés. L'invention concerne également des procédés de mise en culture de cellules et des milieux pour produire de telles immunoglycoprotéines, et des utilisations thérapeutiques de telles immunoglycoprotéines.

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