Materials and methods for treating or preventing...

A - Human Necessities – 61 – K

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A61K 38/46 (2006.01) A61K 9/00 (2006.01) A61P 39/00 (2006.01)

Patent

CA 2696979

A method of treating or preventing organophosphate exposure associated damage in a subject in need thereof is provided. The method comprising providing the subject with a therapeutically effective amount of the acetylcholinesterase splice variant AChE-R ("readthrough" AChE) to thereby. treat the organophosphate exposure associated damage in the subject.

La présente invention concerne un procédé de traitement ou de prévention des dommages liés à l'exposition à un organophosphate chez un sujet qui en a besoin. Le procédé consiste à donner au sujet une quantité thérapeutiquement efficace de la variante d'épissage AChE-R de l'acétylcholinestérase (= translecture = AChE) afin de traiter les dommages associés à l'exposition à un organophosphate chez un sujet.

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