Materials and methods for treating skeletal system damage...

A - Human Necessities – 61 – L

Patent

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A61L 27/38 (2006.01)

Patent

CA 2695863

Disclosed herein are materials and methods suitable for treating injured, damaged or diseased mineralized and non-mineralized skeletal tissues, including bones, joints, tendons, ligaments, cartilage and/or other non-mineralized skeletal tissues. The affected structure can be treated by contacting a surface of the skeletal element at or adjacent to or in the vicinity of an area of injury, damage or disease with an implantable material. The implantable material comprises a biocompatible matrix and cells and is in an amount effective to treat the affected structure. A composition comprising a biocompatible matrix and cells engrafted therein or thereon can be used to treat the affected structure. The composition can be a flexible planar material or a flowable composition.

L'invention concerne des matériaux et des méthodes convenant pour traiter des tissus squelettiques minéralisés et non minéralisés, blessés, endommagés ou malades, y compris des os, des articulations, des tendons, des ligaments, des cartilages et/ou d'autres tissus squelettiques non minéralisés. La structure affectée peut être traitée en mettant en contact une surface de l'élément squelettique sur ou proche ou dans le voisinage d'une zone de blessure, de dommage ou de maladie avec un matériau implantable. Le matériau implantable comprend une matrice biocompatible et des cellules et est présent en une quantité efficace pour traiter la structure affectée. Une composition comprenant une matrice biocompatible et des cellules greffées dedans ou dessus peut être utilisée pour traiter la structure affectée. La composition peut être un matériau plan flexible ou une composition liquide.

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