Materials and methods relating to cancer diagnosis

Details Materials and methods relating to cancer diagnosis Materials and methods relating to cancer diagnosis

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) G01N 33/574 (2006.01) G01N 33/74 (2006.01)

Patent

CA 2477096

The invention provides a number of genetic identifiers (genesets) which may be used as diagnostic tools to determine the presence or risk of breast cancer in a patient. The invention also provides genesets which may be used to classify a breast tumour cell as to its molecular subgroup. Each of the identified genesets may be used to product customised specific nucleic acid microarrays for use in diagnosis and classification of breast tumour cells.

L'invention concerne un certain nombre d'identificateurs génétiques (ensembles géniques ou <=genesets>=) qui peuvent être utilisés en tant qu'outils de diagnostic pour déterminer la présence ou un risque de cancer du sein chez une patiente. Cette invention concerne également des ensembles géniques qui peuvent être utilisés pour la classification d'une cellule tumorale du sein selon son sous-groupe moléculaire. Chaque ensemble génique identifié peut être utilisé pour produire des microréseaux d'acide nucléique spécifiques personnalisés destinés à être utilisés dans le diagnostic et la classification de cellules tumorales du sein.

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