Materials and methods relating to improved vaccination...

A - Human Necessities – 61 – K

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A61K 39/00 (2006.01) A61K 39/12 (2006.01) A61K 39/285 (2006.01) C07K 14/74 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2494304

The invention provides novel vaccination strategies based on a prime-boost vaccination regimen. The inventors have determined improved ways of boosting an immune response in a patient previously primed or exposed to a plurality of epitopes. The improved method requires the epitopes in the boosting phase to be administered individually, i.e. held on separate peptide constructs.

La présente invention concerne de nouvelles stratégies de vaccination fondées sur un régime de vaccination par primo-immunisation/rappel. On a déterminé des manière améliorées d'effectuer le rappel d'une réponse immunitaire chez un patient préalablement primo-immunisé ou exposé à une pluralité d'épitopes. Cette technique améliorée nécessite que les épitopes de la phase de rappel soient administrés individuellement, par exemple portés sur des construits peptidiques distincts.

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